Rashard Mendenhall, RB, Arizona Cardinals
Last week against the Eagles, Mendenhall defiantly took the starting job back from Andre Ellington (who was hurt). Mendenhall received a season-high eighteen carries for 76 yards against an improved Eagle's run defense. This week he gets a Ram's defense that has allowed an average of one touchdown a game to opposing running backs. If Mendenhall gets the same amount of carries as he did last Sunday, he should put in a big week.
Alshon Jeffery, WR, Chicago Bears
This Bears offense may be the second most difficult matchup in the NFL behind the Denver Broncos. Both Jeffery and Brandon Marshall command double teams, they are simply to big, fast, and strong for one defender to handle. The problem is, if you double team them both, all the Bears have to do is hand the ball off to Matt Forte. Thus, most teams choose to double just one of the wideouts and take their chances with the other. Every week it is inevitable that one of them is going to have a huge game, and my guess for this week is Jeffery, who should dominate Morris Claiborne, the Cowboy's underperforming second cornerback.
Joe Flacco, QB, Baltimore Ravens
I don't believe Flacco is a top ten quarterback in the NFL, however, with the right matchup he could be a very productive fantasy play. It is likely that Flacco will be able to shred a miserable Viking's secondary that is worst in the NFL in allowing fantasy points to opposing quarterbacks.
Zac Stacy, RB, St. Louis Rams
Stacy has been an absolute revelation this season for fantasy owners, however this week he should be sitting on your bench with a tough matchup against the Cardinal's defense that is first in the NFL in fantasy points allowed to opposing running backs. Last week this same defense managed to slow down the Eagle's LeSean McCoy, so you should temper your expectations for Stacy.
Marques Colston, WR, New Orleans Saints
Outside of one big week, Colston has been terrible this season, registering over ten fantasy points just twice all year. Fantasy owners just have to accept that Colston is not longer a big part of the Saint's offense. In the red zone Jimmy Graham receives all of the targets, while the Saint's versatile set of running backs gets the attention in the rest of the field. Bottom line, there is no way Colston should be in your lineup any time soon.
Colin Kaepernick, QB, San Francisco 49ers
Though Kaepernick has put together a couple successful weeks in a row now, he will run into a roadblock this weekend against the Seahawk's defense. This outstanding unit has allowed over ten fantasy points to an opposing quarterback just six times this year and none of those performances passed eighteen points. Kaepernick is a solid quarterback, but he won't look one against the Seahawks defense.